Chemistry Paper Supervised by Professor Jin-seok Lee
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- Writer 총관리자
- 보도일자 2012-03-19
The thesis entitled In Vitro Developmental Acceleration of Hippocampal Neurons on Nanostructures of Self-Assembled Silica Beads in Filopodium-Size Ranges written by the research team of Sookmyung’s Department of Chemistry and directed by Professor Jin-seok Lee, was published in the Internet edition of Angewandte Chemie, International Edition on November, 25th.
This SCI is a historic, international journal published by the German company Wiley, and is the world’s most prestigious chemistry-specific journal, having the highest impact factor (12.73) in the area of chemistry.
This study was carried out by the joint research teams in KAIST, such as the team lead by In-sung Choi of the Department of Chemistry, and that lead by Yoon-key Nam of the Department of Bio and Brain Engineering.
The study focused on what effect artificial surface nanostructures have on the development of neurons when they are cultivated on artificial surfaces.
Many studies have been done on how chemicals affect such phenomena as neuronal differentiation, survival, and absorption, but as for the role of the surface structure, its importance has only recently been emphasized.
Especially since it was published that nanostructures on surfaces have an effect on the outgrowth and directional control of neuronal axons, studies of neuron development on various nanostructures combined with the synthesis of nanostructures, which have high degree of freedom in shape and size control, have been noted.
The students Sung-eun Choi (first author and graduate student in his first-semester), and Hee-su Jang (co-author, undergraduate in his third-year), who had leading roles in this study, participated in the Undergraduate Internship Program of Sookmyung University’s Department of Chemistry. The two-year study was finally reported under the guidance of Professor Jin-seok Lee. The two students together with their adviser, Professor Lee, were honored to be registered on the website HANBITSA (literally meaning: people who brought honor to Korea), operated by the Biological Research Information Center.
* Impact Factor: a measure reflecting the average number of citations to articles published in journals.