Professor Jung Su Park’s research team publishes a cover thesis in a renowned chemistry journal
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- Writer 커뮤니케이션팀
- 보도일자 2020-11-13
Professor Jung Su Park’s research team from Department of Chemistry developed the world's first ratiometric fluorescence amplification sensor that generates and emits specific signals depending on the type of explosives. This research is to be published as a cover paper by the internationally recognized scientific journal, “JACS (Journal of the American Chemical Society, IF:14.612).”
According to Professor Park, the development of explosive sensing and detection technology has been actively studied around the world as an important task in terrorist threats and mines detection directly linked to national security. In recent years, attention has been increased, especially due to the environmental and health hazards of Nitro explosives.
<Professor Jung Su Park and the lead author of the paper Ji-yun Lee (from right)>
Molecular and polymer-based explosive detection fluorescence sensors developed to date are characterized by decreasing luminance intensity in response to Nitro-type aromatic explosives such as TNT. However, these luminescence quenching sensors have reduced sensitivity and selectivity, and are particularly vulnerable to false positives.
Accordingly, Professor Jung Su Park succeeded in developing fluorescence indicator displacement assays sensors using a new kind of receptor-fluorescent supermolecular bond. The sensor is capable of amplifying the fluorescence signal by susceptibility to Nitro explosives and showing identifiable ratiometric wavelength changes depending on the type of explosives.
<Mimetic Diagram of the Thesis>
Professor Park explained, “The IDA-based ratiometric fluorescent amplification sensors are more legible and reliable in the sensing and detection of nitro-based explosives compared to conventional sensors that are affected by a variety of factors,” and said, “It is expected to make a breakthrough in the development of small chemical sensor products that ensure excellent chemical selectivity, sensitivity, and low false alarms.”
At the same time, this study was conducted as a mid-career researcher support program promoted by the National Research Foundation of Korea, and is to be published in the Journal of the American Chemical Society, the world's leading authority in chemistry.
Title of Paper: Ratiometric Turn-on Fluorophore Displacement Enembles for Nitroaromatic Explosives Detection (Lead Author, Ji-yun Lee, Master's Course Student of the Department of Chemistry, ‘19)